NEWS: Archive

2013

"Engineering stem cells"
Rigid Growth Matrix - A Key to Success of Cardiac Tissue Engineering: Adult heart muscle is the least regenerative of human tissues. But embryonic cardiomyocytes (cardiac muscle cells) can multiply, with embryonic stem cells providing an endless reservoir for new cardiac tissue. A new study by Nakano, Gimzewski and Stieg at the University of California, Los Angeles (UCLA) suggests that the elasticity of the physical matrix used for growing cardiomyocytes outside of the body may be critical to the success of cardiac tissue engineering efforts.

"Feeling the heat with AFM"
Characterizing pyrolectricity: Through a straightforward modification to a commercially available atomic force microscope, researchers at the California NanoSystems Institute's Nano and Pico Characterization Laboratory (NPC) have demonstrated a method for characterizing the induced pyroelectric effect and resultant polarization distribution with nanoscale precision that is broadly available for any research laboratory. Using a combination of electrostatic force microscopy (EFM) and thermal cycling, this approach combines precise control over the relevant parameters that define the pyroelectric effect with real-space imaging at nanoscale resolution. The article highlights research by Dr. Cristina Martin-Olmos, Dr. Adam Stieg and Prof. James Gimzewski

Squeezing Cancer – Introducing Dr. Shivani Sharma | Asia Research News

In this short introduction, Dr. Shivani Sharma introduces her work and her motivation for entering this field.
This is the first in a series of short introductions of various scientists I have had the pleasure of meeting. It is my hope that these videos will shed some light on the life of scientists, what they do and why they do it. Rest assured: it is not for the money!

"Correlative Microscopy"
By combining cellular force spectroscopy with super-resolution confocal microscopy (STED) researchers at the NPC and ALM Core Laboratories, in collaboration with the UCLA School of Medicine, have gained novel insights into mechanisms of drug resistance in ovarian cancer cells.

2012

"Novel Computational Architectures"
At the Edge of Chaos - A New Type of Computing: How do we take the next step in computing? When can we stop teaching our computers using software and programming? Can we build a network of parts that make a greater whole? A whole in which new and unexpected patterns of learning and prediction emerge, like the spontaneous movements of flocking birds. Conventional computing is slowed down by log-jams at the “von Neumann bottleneck”, as instructions and data are shuttled back and forth between memory and processor cores. In a recent paper, Adam. Z. Stieg and co-workers explain how a promising new type of computing apes biological systems and avoids information bottlenecks.

2011

"Forces and Cancer"
Novel Detection: Researchers probe the mechanics of tumor cells with atomic force microscopy and explore the technique as a diagnostic tool by Lauren K. Wolf, May 29, 2011. The article highlights research by Prof. Gimzewski and Dr. Rao of the Medical School using AFM as a new diagnostic tool for disease.

"Wiring a Single Molecule Circuit"
Electronics: Researchers link polymer nanowires to single molecules by Lauren K. Wolf, May 13, 2011. The article highlights research by Prof. Gimzewski in collaboration with the National Institute of Materials Science, Tsukuba, Japan.

"Drug Resistance"
Probing Cancer ACS Meeting News: Atomic force microscopy could yield new insights from observed changes in treated cancer cells by Lauren K. Wolf, March 31, 2011 The article highlights research by Prof. Gimzewski and Shivani Sharma of the NPC in collaboration with Dr. Rao of the Medical School.